The South American trio of Lionel Messi, Neymar and Luis Suarez reached a scorching 108 goals for the season following the La Liga leaders' 8-0 destruction of Cordoba on Saturday but the team's defence is yet to dispel doubts
Barcelona and Atletico Madrid led a Spanish Armada into the Champions League last 16 with home wins on Wednesday and in-form Aaron Ramsey steadied Arsenal's boat with a battling win against rocky Borussia Dortmund.
It was a day of role reversal as Jose Mourinho's often cautious Chelsea thumped Everton 6-3 in a thriller on Saturday while champions Manchester City's attacking talents were blunted in a shock 1-0 home defeat by Stoke City.
Napoli's Marek Hamsik enjoyed a memorable return to his former club Slovan Bratislava, scoring one and creating another, in a 2-0 victory on Thursday as the Italians joined five others who made it two wins from two in the Europa League group stage.
Chelsea scrambled a stoppage-time winner to snatch a 1-0 victory over Everton on Saturday, showing their Premier League title mettle by claiming three points when they looked on course to suffer another damaging blow.
Real Madrid and Barcelona pulled two points clear in La Liga when Cristiano Ronaldo set a club scoring record in Real's 3-0 stroll against Levante and Neymar hit four as Barca beat Rayo Vallecano 5-2 on Saturday.
Juventus defeated second-placed Lazio 2-0 at home on Saturday to take another huge step towards their fourth straight Serie A title and boost their confidence for Wednesday's crunch Champions League clash in Monaco.
Ahead of their high-profile clash on Saturday, check out the five standout clashes between Arsenal and Chelsea.
He increasingly looks like a manager unable to cope with the modern tactical realities of football. His display of a fear of failure has been appalling to watch. But Mourinho getting the sack at this juncture will hardly solve the problem, says Dhruv Munjal.
If reports are to be believed, it is a video posted online that has got the Portuguese's goat. According to the European press, Canal Plus, a French TV channel put up a video where Mourinho has questioned the quality of strikers in his Chelsea squad.
Rafael Nadal has withdrawn from the Paris Masters ahead of the tournament's start on Monday for "personal reasons", the French Tennis Federation announced on Friday.